Relative Risk vs Absolute Risk in Nutrition News
Quick answer: Relative risk tells you how much a risk changed compared with where it started. Absolute risk tells you how many people out of 100 or 1,000 were actually affected. "Lowers cancer risk 8%" is relative. If the starting risk is small, an 8% cut is a very small number of people. Before you change anything because of a headline, ask: 8% of what?
On this page
- The two numbers
- A worked example: the multivitamin trial
- Fiber: when relative numbers stack up
- The same trick with weight loss
- How to convert a headline
- What the research says
- KetoDick's take
- Key takeaways
- Related
The two numbers
Say a risk goes from 2 in 100 to 1 in 100.
- Relative risk reduction: 50%. The risk halved.
- Absolute risk reduction: 1 percentage point. One person in 100 was spared.
Both are true. The first makes a better headline. The second tells you what it means for you.
Papers often report a hazard ratio (HR). An HR of 0.92 means the event happened at about 92% of the rate in the comparison group, which a headline turns into "8% lower risk". An HR of 1.06 becomes "6% higher risk".
A worked example: the multivitamin trial
The Physicians' Health Study II gave 14,641 male physicians aged 50 and up either a daily multivitamin or a placebo, for a median of 11.2 years. Total cancer came in with a hazard ratio of 0.92 (Gaziano et al., 2012). That's a real, randomized result, and it's where "multivitamins cut cancer risk 8%" comes from.
Now the arithmetic. The numbers below are made up to show the method, not taken from the trial:
- Suppose 100 men in every 1,000 got cancer over the study in the placebo group.
- An 8% relative cut takes that to about 92 in 1,000.
- That's 8 fewer cases per 1,000 men, or 0.8 percentage points.
- Flip it: about 125 men take the pill for the whole period for one of them to avoid a cancer (1,000 ÷ 8).
If the starting risk were lower, say 20 in 1,000, the same 8% would be under 2 cases per 1,000. Same headline, very different meaning. That's why you need the starting rate, which is in the paper, not the press release.
Fiber: when relative numbers stack up
Fiber research is full of relative numbers, mostly from observational studies:
- Each extra 10 g a day of fiber was associated with about 10% lower colorectal cancer risk (Aune et al., 2011).
- Each extra 7 g a day was associated with 9% lower cardiovascular and coronary heart disease risk (Threapleton et al., 2013).
- Highest versus lowest fiber intake was associated with 15–30% lower all-cause and cardiovascular death, heart disease, stroke, type 2 diabetes and colorectal cancer, with the largest reductions at 25–29 g a day (Reynolds et al., 2019).
Two things to notice. First, these are associations, so people who eat more fiber may differ in other ways. Second, the "per 10 g" phrasing is a slope, and the absolute effect depends on your own starting risk, which depends on your age, family history and everything else.
It's still a consistent signal across many outcomes, which is a good reason not to let fiber disappear on a low-carb diet. It just isn't a promise that 10 g of fiber removes 10% of anything for you personally.
The same trick with weight loss
Relative framing isn't only for disease. In DIETFITS, the healthy low-carb group lost about 6.0 kg in a year and the healthy low-fat group about 5.3 kg, a difference that wasn't significant (Gardner et al., 2018).
Do the division and low-carb lost about 13% more. That sounds like a win. In absolute terms it's about 0.7 kg, or a pound and a half, over twelve months. That's the size of an ordinary swing in water weight.
So what you do is ask for the absolute difference every time, whether the claim flatters your diet or not.
How to convert a headline
- Find the relative number. "Cuts risk 8%", "HR 0.92", "doubles the risk".
- Find the starting rate. How many people per 100 or 1,000 had the outcome in the comparison group? It's in the paper's results or tables.
- Multiply. Starting rate × relative change = absolute change.
- Check who was studied. Older men? Women 30–60? People with diabetes?
- Check the design. Randomized trial or observational? Observational relative risks can't show cause on their own.
A "doubled" risk of something rare can still be rare. A "small" relative drop in something common can matter a lot.
What the research says
The papers above show both kinds of number at work:
- Randomized, small relative benefit: PHS II, total cancer HR 0.92 over a median 11.2 years in 14,641 men (Gaziano et al., 2012).
- Observational, small relative harm: in the Iowa Women's Health Study of 38,772 older women, multivitamin use was associated with slightly higher total mortality, HR 1.06 (Mursu et al., 2011). Same pill, opposite direction, different design. That's a good illustration of why one observational HR shouldn't change what you do.
- Consistent observational fiber signals across colorectal cancer, heart disease and mortality (Aune et al., 2011; Threapleton et al., 2013; Reynolds et al., 2019).
KetoDick's take
He hasn't made a video about relative risk as such, but the habit this article asks for is his. Back-of-envelope arithmetic is a habit of his; he's worked out that a 100 lb person at 10% body fat still carries about 35,000 kcal of stored fat, to show where the energy comes from in the weight-loss phase (video NUJNFG6lLWw).
He's also said he'll find people actual studies when asked, so they can decide for themselves whether it was too few people or too old a study (video xyEZL0HuejI). And he's told viewers to use Google Scholar or add "PubMed" to a search, because a study has to state its protocol (video 1JbK1_ClDmY). Those are exactly the places to find the starting rates a headline leaves out.
Key takeaways
- Relative risk: change compared with the start. Absolute risk: how many people per 100 or 1,000.
- HR 0.92 means "8% lower" relative, which can be a small absolute number.
- You need the starting rate to convert; it's in the paper, not the headline.
- Fiber's relative numbers are consistent but observational.
- DIETFITS: "13% more weight loss" was about 0.7 kg in a year.
- Ask who was studied and whether it was a trial.
Related
- Guide: Nutrition science for normal people · Reading nutrition headlines · How to read a study · Observational studies vs trials
- Blog: The multivitamin memory study · Do multivitamins work? · Soluble vs insoluble fiber · The DIETFITS study explained · How to search PubMed for diet studies
- Videos: Common beginner questions about keto · Men's Health hack job on keto